ADAR1

Double-stranded RNA-specific adenosine deaminase

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    Description

    ADAR1 is a protein with 136 kDa. Has various molecular functions, such as DNA binding. Is involved in several biological processes, including cellular response to virus.

     

     

     

     

     

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    Details
    • Complete Protein Name
      Double-stranded RNA-specific adenosine deaminase
    • Gene ID
      103
    • Uniprot ID
      P55265
    • Chromossomal Location
      1q21.3
    • RNA-binding protein
      Yes
    • Molecular Function
      DNA binding, double-stranded RNA adenosine deaminase activity, metal ion binding, RNA binding
    • OMIM Disease
      Aicardi-Goutieres syndrome ; Dyschromatosis symmetrica hereditaria
    • Used cell type
      HeLa
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Nucleus, cytoplasm
    • Reference
      Weissbach R., Scadden ADJ. (2012). Tudor-SN and ADAR1 are components of cytoplasmic stress granules. RNA. 2012;18(3):462-471
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