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    ALDH18A1

    Delta-1-pyrroline-5-carboxylate synthase

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      Description

      ALDH18A1 is an enzyme with 87 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including glutamate metabolic process.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Delta-1-pyrroline-5-carboxylate synthase
      • Gene ID
        5832
      • Uniprot ID
        P54886
      • Chromossomal Location
        10q24.1
      • RNA-binding protein
        Yes
      • Molecular Function
        ATP binding, delta1-pyrroline-5-carboxylate synthetase ,glutamate 5-kinase activity, glutamate-5-semialdehyde dehydrogenase activity , identical protein binding ,RNA binding
      • OMIM Disease
        Cutis laxa, type IIIA; Spastic paraplegia
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Mitochondrion inner membrane
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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