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    APOBEC3G

    DNA dC->dU-editing enzyme APOBEC-3G

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      Description

      APOBEC3G is a DNA deaminase with 46 kDa. Has various molecular functions, such as cytidine deaminase activity. Is involved in several biological processes, including innate immune response.

       

       

       

       

       

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      Details
      • Complete Protein Name
        DNA dC->dU-editing enzyme APOBEC-3G
      • Gene ID
        60489
      • Uniprot ID
        Q9HC16
      • Chromossomal Location
        22q13.1
      • RNA-binding protein
        Yes
      • Molecular Function
        Cytidine deaminase activity, dCTP deaminase activity, deoxycytidine deaminase activity ,protein homodimerization activity, RNA binding , zinc ion binding
      • Used cell type
        HEK293T, HeLa-CD4; human leukemic T cell lines H9
      • Used Stimuli
        Sodium arsenite, cyanide
      • Subcellular Localization
        Nucleus, Cytoplasm, P-body
      • Reference
        Kozak,S.; Marin,M.; Rose,K; Bystrom,C.; Kabat,D. (2006). The anti-HIV-1 editing enzyme APOBEC3G binds HIV-1 RNA and messenger RNAs that shuttle between polysomes and stress granules. J. Biol. Chem. 281, 29105– 29119
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