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    CDC73

    Parafibromin

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      Description

      CDC73 is a tumor suppressor with 60 kDa. Has various molecular functions, such as RNA polymerase II core binding. Is involved in several biological processes, including cell cycle.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Parafibromin
      • Gene ID
        79577
      • Uniprot ID
        Q6P1J9
      • Chromossomal Location
        1q31.2
      • RNA-binding protein
        No
      • Molecular Function
        RNA polymerase II core binding, transcription factor activity, RNA polymerase II transcription factor binding
      • OMIM Disease
        Hyperparathyroidism, familial ; Hyperparathyroidism-jaw tumor syndrome; Parathyroid adenoma with cystic changes; Parathyroid carcinoma
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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