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    CIT

    Citron Rho-interacting kinase

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      Description

      CIT is a protein with 231 kDa. Has various molecular functions, such as metal ion binding. Is involved in several biological processes, including G2/M transition of mitotic cell cycle.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Citron Rho-interacting kinase
      • Gene ID
        11113
      • Uniprot ID
        O14578
      • Chromossomal Location
        12q24.23
      • RNA-binding protein
        No
      • Molecular Function
        ATP binding ,metal ion binding ,PDZ domain binding ,protein serine/threonine kinase activity,Rho GTPase binding ,scaffold protein binding ,SH3 domain binding
      • OMIM Disease
        Microcephaly
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Cytoplasm
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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