MSH6

DNA mismatch repair protein Msh6

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    Description

    MSH6 is a protein with 152 kDa. Has various molecular functions, such as chromatin binding. Is involved in several biological processes, including DNA repair.

     

     

     

     

     

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    Details
    • Complete Protein Name
      DNA mismatch repair protein Msh6
    • Gene ID
      2956
    • Uniprot ID
      P52701
    • Chromossomal Location
      2p16.3
    • RNA-binding protein
      No
    • Molecular Function
      ATP binding ,chromatin binding ,damaged DNA binding ,DNA-dependent ATPase activity ,guanine/thymine mispair binding ,methylated histone binding ,mismatched DNA binding
    • OMIM Disease
      Colorectal cancer, Endometrial cancer, Mismatch repair cancer syndrome
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Nucleus, Chromosome
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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