MAP4K4

Mitogen-activated protein kinase kinase kinase kinase 4

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    Description

    MAP4K4 is a serine/threonine kinase with 142 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including negative regulation of apoptotic process.

     

     

     

     

     

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    Categories
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    Details
    • Complete Protein Name
      Mitogen-activated protein kinase kinase kinase kinase 4
    • Gene ID
      9448
    • Uniprot ID
      O95819
    • Chromossomal Location
      2q11.2
    • RNA-binding protein
      No
    • Molecular Function
      ATP binding , creatine kinase activity ,MAP kinase kinase kinase kinase activity , protein serine/threonine kinase activity
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Cytoplasm
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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