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    MAP2K7

    Dual specificity mitogen-activated protein kinase kinase 7

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      Description

      MAP2K7 is a dual specificity protein kinase with 47 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including apoptotic process.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Dual specificity mitogen-activated protein kinase kinase 7
      • Gene ID
        5609
      • Uniprot ID
        O14733
      • Chromossomal Location
        19p13.2
      • RNA-binding protein
        No
      • Molecular Function
        ATP binding ,enzyme binding ,magnesium ion binding ,MAP kinase kinase activity ,protein kinase binding ,protein phosphatase binding ,protein serine/threonine kinase activity ,protein tyrosine kinase activity
      • Used cell type
        A172
      • Used Stimuli
        UV irradiation, heat shock
      • Subcellular Localization
        Nucleus, Cytoplasm
      • Reference
        Sakurai,M.; Shirimoto,Y.; Ota,H.;Song,C.; Kossenkov,A.; Wickramasinghe,J.; Showe,L.; Skordalakes,E.; Tang,H.; Speicher,D.; Nishikura,K. (2017). ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay. Nat Struct Mol Biol. 24(6):534-543
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