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    LMNA

    Prelamin-A/C

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      Description

      LMNA is a protein with 74 kDa. Has various molecular functions, such as identical protein binding. Is involved in several biological processes, including mitotic nuclear envelope reassembly.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Prelamin-A/C
      • Gene ID
        4000
      • Uniprot ID
        P02545
      • Chromossomal Location
        1q22
      • RNA-binding protein
        No
      • Molecular Function
        Identical protein binding ,structural molecule activity
      • OMIM Disease
        Cardiomyopathy, Charcot-Marie-Tooth disease, Emery-Dreifuss muscular dystrophy, Heart-hand syndrome, Hutchinson-Gilford progeria, Lipodystrophy, Malouf syndrome, Mandibuloacral dysplasia, Muscular dystrophy, Restrictive dermopathy
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus, Nucleus envelope, Nucleus lamina, nucleoplasm
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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