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    LBR

    Lamin-B receptor

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      Description

      LBR is a protein with 70 kDa. Has various molecular functions, such as DNA binding. Is involved in several biological processes, including cholesterol biosynthetic process.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Lamin-B receptor
      • Gene ID
        3930
      • Uniprot ID
        Q14739
      • Chromossomal Location
        1q42.12
      • RNA-binding protein
        Yes
      • Molecular Function
        Chromo shadow domain binding, delta14-sterol reductase activity, DNA binding, lamin binding ,oxidoreductase activity, acting on the CH-CH group of donors, RNA binding
      • OMIM Disease
        Reynolds syndrome, Greenberg skeletal dysplasia, Pelger-Huet anomaly
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus inner membrane, Multi-pass membrane protein
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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