LBR

Lamin-B receptor

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    Description

    LBR is a protein with 70 kDa. Has various molecular functions, such as DNA binding. Is involved in several biological processes, including cholesterol biosynthetic process.

     

     

     

     

     

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    Details
    • Complete Protein Name
      Lamin-B receptor
    • Gene ID
      3930
    • Uniprot ID
      Q14739
    • Chromossomal Location
      1q42.12
    • RNA-binding protein
      Yes
    • Molecular Function
      Chromo shadow domain binding, delta14-sterol reductase activity, DNA binding, lamin binding ,oxidoreductase activity, acting on the CH-CH group of donors, RNA binding
    • OMIM Disease
      Reynolds syndrome, Greenberg skeletal dysplasia, Pelger-Huet anomaly
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Nucleus inner membrane, Multi-pass membrane protein
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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