KANK2

KN motif and ankyrin repeat domain-containing protein 2

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    Description

    KANK2 is a protein with 91 kDa. Is involved in several biological processes, including apoptotic process.

     

     

     

     

     

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    Details
    • Complete Protein Name
      KN motif and ankyrin repeat domain-containing protein 2
    • Gene ID
      25959
    • Uniprot ID
      Q63ZY3
    • Chromossomal Location
      19p13.2
    • RNA-binding protein
      No
    • Molecular Function
      Apoptotic process ,negative regulation of cell proliferation ,negative regulation of G1/S transition of mitotic cell cycle, negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of programmed cell death ,negative regulation of transcription from RNA polymerase II promoter ,negative regulation of vitamin D receptor signaling pathway ,transcription, DNA-templated
    • OMIM Disease
      Nephrotic syndrome, Palmoplantar keratoderma and woolly hair
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Mitochondrion, Cytoplasm
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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