KN motif and ankyrin repeat domain-containing protein 2
Gene ID
25959
Uniprot ID
Q63ZY3
Chromossomal Location
19p13.2
RNA-binding protein
No
Molecular Function
Apoptotic process ,negative regulation of cell proliferation ,negative regulation of G1/S transition of mitotic cell cycle, negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of programmed cell death ,negative regulation of transcription from RNA polymerase II promoter ,negative regulation of vitamin D receptor signaling pathway ,transcription, DNA-templated
OMIM Disease
Nephrotic syndrome, Palmoplantar keratoderma and woolly hair
Used cell type
U-2 OS
Used Stimuli
Sodium arsenite
Subcellular Localization
Mitochondrion, Cytoplasm
Reference
Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498