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    IGF2BP3

    Insulin-like growth factor 2 mRNA-binding protein 3

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      Description

      IGF2BP3 is a RNA-binding factor with 63 kDa. Has various molecular functions, such as RNA binding. Is involved in several biological processes, including negative regulation of translation.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Insulin-like growth factor 2 mRNA-binding protein 3
      • Gene ID
        10643
      • Uniprot ID
        O00425
      • Chromossomal Location
        7p15.3
      • RNA-binding protein
        Yes
      • Molecular Function
        mRNA 3'-UTR binding,mRNA 5'-UTR binding,RNA binding ,translation regulator activity
      • Used cell type
        SK-N-BE(2)C, MDA-MB-231
      • Used Stimuli
        Heat shock, arsenic trioxide
      • Subcellular Localization
        Nucleus, Cytoplasm
      • Reference
        Kobayashi,T.; Winslow,S.; Sunesson,L.; Hellman,U.; Larsson,C .(2012). PKCα Binds G3BP2 and Regulates Stress Granule Formation Following Cellular Stress. PLoS One. 2012;7(4):e35820
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