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    IGF2BP1

    Insulin-like growth factor 2 mRNA-binding protein 1

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      Description

      IGF2BP1 is a RNA-binding factor with 63 kDa. Has various molecular functions, such as mRNA 3'-UTR binding. Is involved in several biological processes, including neuronal stem cell population maintenance.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Insulin-like growth factor 2 mRNA-binding protein 1
      • Gene ID
        10642
      • Uniprot ID
        Q9NZI8
      • Chromossomal Location
        17q21.32
      • RNA-binding protein
        Yes
      • Molecular Function
        mRNA 3'-UTR binding ,mRNA 5'-UTR binding ,mRNA binding ,RNA binding ,translation regulator activity
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus, Cytoplasm, perinuclear region, lamellipodium, dendrite, dendritic spine, growth cone, filopodium, axon
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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