HNRNPK is a protein with 50 kDa. Has various molecular functions, such as cadherin binding. Is involved in several biological processes, including negative regulation of mRNA splicing, via spliceosome.
Cadherin binding ,identical protein binding ,protein domain specific binding ,RNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding , single-stranded DNA binding , transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
OMIM Disease
Au-Kline syndrome
Used cell type
U-2 OS
Used Stimuli
Sodium arsenite
Subcellular Localization
Nucleus, Cytoplasm, podosome
Reference
Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498