HNRNPK

Heterogeneous nuclear ribonucleoprotein K

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    Description

    HNRNPK is a protein with 50 kDa. Has various molecular functions, such as cadherin binding. Is involved in several biological processes, including negative regulation of mRNA splicing, via spliceosome.

     

     

     

     

     

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    Details
    • Complete Protein Name
      Heterogeneous nuclear ribonucleoprotein K
    • Gene ID
      3190
    • Uniprot ID
      P61978
    • Chromossomal Location
      9q21.32
    • RNA-binding protein
      Yes
    • Molecular Function
      Cadherin binding ,identical protein binding ,protein domain specific binding ,RNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding , single-stranded DNA binding , transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
    • OMIM Disease
      Au-Kline syndrome
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Nucleus, Cytoplasm, podosome
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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