HMGA1

High mobility group protein HMG-I/HMG-Y

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    Description

    HMGA1 is a protein with 11 kDa. Has various molecular functions, such as chromatin binding. Is involved in several biological processes, including base-excision repair.

     

     

     

     

     

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    Details
    • Complete Protein Name
      High mobility group protein HMG-I/HMG-Y
    • Gene ID
      3159
    • Uniprot ID
      P17096
    • Chromossomal Location
      6p21.31
    • RNA-binding protein
      No
    • Molecular Function
      5'-deoxyribose-5-phosphate lyase activity , AT DNA binding , chromatin binding, DNA-(apurinic or apyrimidinic site) lyase activity ,DNA binding , enhancer sequence-specific DNA binding , enzyme binding , ligand-dependent nuclear receptor transcription coactivator activity , peroxisome proliferator activated receptor binding , retinoic acid receptor binding , retinoid X receptor binding , transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding , transcription factor activity, sequence-specific DNA binding , transcription factor binding
    • OMIM Disease
      Susceptibility to Diabetes mellitus
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Nucleus, Chromosome
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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