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    HMGA1

    High mobility group protein HMG-I/HMG-Y

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      Description

      HMGA1 is a protein with 11 kDa. Has various molecular functions, such as chromatin binding. Is involved in several biological processes, including base-excision repair.

       

       

       

       

       

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      Details
      • Complete Protein Name
        High mobility group protein HMG-I/HMG-Y
      • Gene ID
        3159
      • Uniprot ID
        P17096
      • Chromossomal Location
        6p21.31
      • RNA-binding protein
        No
      • Molecular Function
        5'-deoxyribose-5-phosphate lyase activity , AT DNA binding , chromatin binding, DNA-(apurinic or apyrimidinic site) lyase activity ,DNA binding , enhancer sequence-specific DNA binding , enzyme binding , ligand-dependent nuclear receptor transcription coactivator activity , peroxisome proliferator activated receptor binding , retinoic acid receptor binding , retinoid X receptor binding , transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding , transcription factor activity, sequence-specific DNA binding , transcription factor binding
      • OMIM Disease
        Susceptibility to Diabetes mellitus
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus, Chromosome
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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