GSPT1

Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

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    Description

    GSPT1 is a protein with 55 kDa. Has various molecular functions, such as GTP binding. Is involved in several biological processes, including cytoplasmic translational termination.

     

     

     

     

     

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    Details
    • Complete Protein Name
      Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
    • Gene ID
      2935
    • Uniprot ID
      P15170
    • Chromossomal Location
      16p13.13
    • RNA-binding protein
      Yes
    • Molecular Function
      GTPase activity, GTP binding, RNA binding, translation release factor activity
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Cytosol, intracellular, translation release factor complex
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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