FLNB

Filamin-B

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    Description

    FLNB is a protein with 278 kDa. Has various molecular functions, such as cadherin binding. Is involved in several biological processes, including actin cytoskeleton organization.

     

     

     

     

     

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    Details
    • Complete Protein Name
      Filamin-B
    • Gene ID
      2317
    • Uniprot ID
      O75369
    • Chromossomal Location
      3p14.3
    • RNA-binding protein
      Yes
    • Molecular Function
      Actin binding ,cadherin binding ,identical protein binding ,RNA binding
    • OMIM Disease
      Atelosteogenesis, Boomerang dysplasia, Larsen syndrome, Spondylocarpotarsal synostosis syndrome
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Cytoskeleton, cell cortex, Z line
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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