FBL

rRNA 2-O-methyltransferase fibrillarin

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    Description

    FBL is a S-adenosyl-L-methionine-dependent methyltransferase with 33 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including osteoblast differentiation.

     

     

     

     

     

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    Categories
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    Details
    • Complete Protein Name
      rRNA 2-O-methyltransferase fibrillarin
    • Gene ID
      2091
    • Uniprot ID
      P22087
    • Chromossomal Location
      19q13.2
    • RNA-binding protein
      Yes
    • Molecular Function
      Methyltransferase activity, RNA binding
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Nucleus
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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