UPF1

Regulator of nonsense transcripts 1

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    Description

    UPF1 is an RNA-dependent helicase and ATPase with 124 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including cell cycle phase transition.

     

     

     

     

     

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    Categories
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    Details
    • Complete Protein Name
      Regulator of nonsense transcripts 1
    • Gene ID
      5976
    • Uniprot ID
      Q92900
    • Chromossomal Location
      19p13.11
    • RNA-binding protein
      Yes
    • Molecular Function
      ATP binding ,ATP-dependent RNA helicase activity ,chromatin binding ,helicase activity ,RNA binding ,telomeric DNA binding ,zinc ion binding
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Nucleus, Cytoplasm, P-body
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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