TRIM21

E3 ubiquitin-protein ligase TRIM21

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    Description

    TRIM21 is an E3 ubiquitin-protein ligase with 54 kDa. Has various molecular functions, such as DNA binding. Is involved in several biological processes, including cell cycle.

     

     

     

     

     

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    Categories
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    Details
    • Complete Protein Name
      E3 ubiquitin-protein ligase TRIM21
    • Gene ID
      6737
    • Uniprot ID
      P19474
    • Chromossomal Location
      11p15.4
    • RNA-binding protein
      Yes
    • Molecular Function
      DNA binding ,identical protein binding ,RNA binding ,ubiquitin-protein transferase activity ,zinc ion binding
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Nucleus, Cytoplasm, autophagosome, P-body
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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