TPM1

Tropomyosin alpha-1 chain

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    Description

    TPM1 is a protein with 32 kDa. Has various molecular functions, such as actin binding. Is involved in several biological processes, including cytoskeleton organization.

     

     

     

     

     

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    Details
    • Complete Protein Name
      Tropomyosin alpha-1 chain
    • Gene ID
      7168
    • Uniprot ID
      P09493
    • Chromossomal Location
      15q22.2
    • RNA-binding protein
      No
    • Molecular Function
      Actin binding ,actin filament binding ,cytoskeletal protein binding ,identical protein binding ,protein heterodimerization activity ,protein homodimerization activity ,structural constituent of cytoskeleton ,structural constituent of muscle
    • OMIM Disease
      Cardiomyopathy, Left ventricular noncompaction
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Cytoskeleton
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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