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    ZC3H12A

    Endoribonuclease ZC3H12A

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      Description

      ZC3H12A is an endoribonuclease with 65 kDa. Has various molecular functions, such as ribosome binding. Is involved in several biological processes, including angiogenesis.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Endoribonuclease ZC3H12A
      • Gene ID
         80149
      • Uniprot ID
        Q5D1E8
      • Chromossomal Location
        1p34.3
      • RNA-binding protein
        Yes
      • Molecular Function
        Chromatin binding ,DNA binding ,endoribonuclease activity ,exoribonuclease activity ,metal ion binding ,miRNA binding ,mRNA 3'-UTR AU-rich region binding ,mRNA 3'-UTR binding ,mRNA binding ,ribonuclease activity ,ribosome binding ,RNA binding ,RNA stem-loop binding
      • Used cell type
        RAW 264.7, HeLa, HEK293, MEFs, THP-1
      • Used Stimuli
        Sodium arsenite, heat shock
      • Subcellular Localization
        Endoplasmic reticulum, Nucleus, Cytoplasm, P-body, Cytoplasmic granule
      • Reference
        Qi, D.; Huang, S.; Miao, R.; She, Z.-G.; Quinn, T.; Chang, Y.; Liu, J.; Fan, D.; Chen, Y. E.; Fu, M. (2011). Monocyte Chemotactic Protein-induced Protein 1 (MCPIP1) Suppresses Stress Granule Formation and Determines Apoptosis under Stress. The Journal of Biological Chemistry, 286(48), 41692–41700
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