TIAR

TIA-1-related

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    Description

    TIAR is an RNA-binding protein with 41 kDa. Has various molecular functions, such as AU-rich element binding. Is involved in several biological processes, including germ cell development.

     

     

     

     

     

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    Categories
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    Details
    • Complete Protein Name
      TIA-1-related
    • Gene ID
      7073
    • Uniprot ID
      Q01085
    • Chromossomal Location
      10q26.11
    • RNA-binding protein
      Yes
    • Molecular Function
      AU-rich element binding ,DNA binding ,RNA binding
    • Used cell type
      DU145, COS-7, HeLa
    • Used Stimuli
      Sodium arsenite, heat shock, sorbitol, UV irradiation
    • Subcellular Localization
      Nucleus, Cytoplasm, Cytoplasmic granule
    • Reference
      Kedersha, N. L.; Gupta, M.; Li, W.; Miller, I.; Anderson, P. (1999). RNA-Binding Proteins Tia-1 and Tiar Link the Phosphorylation of Eif-2α to the Assembly of Mammalian Stress Granules. The Journal of Cell Biology, 147(7), 1431–1442
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