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    TIAR

    TIA-1-related

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      Description

      TIAR is an RNA-binding protein with 41 kDa. Has various molecular functions, such as AU-rich element binding. Is involved in several biological processes, including germ cell development.

       

       

       

       

       

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      Details
      • Complete Protein Name
        TIA-1-related
      • Gene ID
        7073
      • Uniprot ID
        Q01085
      • Chromossomal Location
        10q26.11
      • RNA-binding protein
        Yes
      • Molecular Function
        AU-rich element binding ,DNA binding ,RNA binding
      • Used cell type
        DU145, COS-7, HeLa
      • Used Stimuli
        Sodium arsenite, heat shock, sorbitol, UV irradiation
      • Subcellular Localization
        Nucleus, Cytoplasm, Cytoplasmic granule
      • Reference
        Kedersha, N. L.; Gupta, M.; Li, W.; Miller, I.; Anderson, P. (1999). RNA-Binding Proteins Tia-1 and Tiar Link the Phosphorylation of Eif-2α to the Assembly of Mammalian Stress Granules. The Journal of Cell Biology, 147(7), 1431–1442
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