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    STAT1

    Signal transducer and activator of transcription 1-alpha/beta

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      Description

      STAT1 is a protein with 87 kDa. Has various molecular functions, such as cadherin binding. Is involved in several biological processes, including blood circulation.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Signal transducer and activator of transcription 1-alpha/beta
      • Gene ID
        6772
      • Uniprot ID
        P42224
      • Chromossomal Location
        2q32.2
      • RNA-binding protein
        No
      • Molecular Function
        Cadherin binding ,core promoter binding ,double-stranded DNA binding ,enzyme binding ,histone acetyltransferase binding ,histone binding ,identical protein binding ,nuclear hormone receptor binding ,promoter-specific chromatin binding ,protein homodimerization activity ,repressing transcription factor binding ,RNA polymerase II core promoter proximal region sequence-specific DNA binding ,RNA polymerase II core promoter sequence-specific DNA binding ,signal transducer activity ,transcription factor activity, RNA polymerase II core promoter sequence-specific ,transcription factor activity, sequence-specific DNA binding ,tumor necrosis factor receptor binding ,ubiquitin-like protein ligase binding
      • OMIM Disease
        Immunodeficiency (mycobacteriosis, mycobacterial and viral infections)
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus, Cytoplasm
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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