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    NCOA3

    Nuclear receptor coactivator 3

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      Description

      NCOA3 is a nuclear receptor coactivator with 155 kDa. Has various molecular functions, such as androgen receptor binding. Is involved in several biological processes, including cell dedifferentiation.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Nuclear receptor coactivator 3
      • Gene ID
        8202
      • Uniprot ID
        Q9Y6Q9
      • Chromossomal Location
        20q13.12
      • RNA-binding protein
        Yes
      • Molecular Function
        Androgen receptor binding ,disordered domain specific binding ,histone acetyltransferase activity ,ligand-dependent nuclear receptor binding ,ligand-dependent nuclear receptor transcription coactivator activity , nuclear hormone receptor binding ,protein heterodimerization activity ,protein N-terminus binding ,thyroid hormone receptor binding ,transcription coactivator activity
      • Used cell type
        HeLa
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus, Cytoplasm
      • Reference
        Yu, C.; York, B.; Wang, S.; Feng, Q.; Xu, J.; O’Malley, B. W. (2007). An Essential Function of the SRC-3 Coactivator in Suppression of Cytokine mRNA Translation and Inflammatory Response. Molecular Cell, 25(5), 765–778
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