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    SMN

    Survival motor neuron protein

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      Description

      SMN is a protein with 31 kDa. Has various molecular functions, such as RNA binding. Is involved in several biological processes, including nervous system development.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Survival motor neuron protein
      • Gene ID
        6606
      • Uniprot ID
        Q16637
      • Chromossomal Location
        5q13.2
      • RNA-binding protein
        Yes
      • Molecular Function
        Identical protein binding ,RNA binding
      • OMIM Disease
        Spinal muscular atrophy
      • Used cell type
        HeLa, SKN-MC, human SMA type I fibroblasts (3813 and 9677), IMR-91
      • Used Stimuli
        UV irradiation, sodium arsenite, heat shock
      • Subcellular Localization
        Nucleus, Cytoplasm, Cytoplasmic granule, Perikaryon, Cell projection, Z line
      • Reference
        Hua, Y.; Zhou, J. (2004). Survival motor neuron protein facilitates assembly of stress granules. FEBS Lett. 572(1-3):69-74
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