RPS6KA3

Ribosomal protein S6 kinase alpha-3

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    Description

    RPS6KA3 is a serine/threonine-protein kinase with 83 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including cell cycle.

     

     

     

     

     

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    Details
    • Complete Protein Name
      Ribosomal protein S6 kinase alpha-3
    • Gene ID
       6197
    • Uniprot ID
      P51812
    • Chromossomal Location
      Xp22.12
    • RNA-binding protein
      No
    • Molecular Function
      ATP binding ,cysteine-type endopeptidase inhibitor activity involved in apoptotic process ,kinase activity ,magnesium ion binding ,protein kinase activity ,protein kinase binding ,protein serine/threonine kinase activity
    • OMIM Disease
      Coffin-Lowry syndrome, Mental retardation
    • Used cell type
      MCF-7, T47D, MCF-10A, MDA-MB231, HME
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Nucleus, Cytoplasm
    • Reference
      Eisinger-Mathason, T. S. K.; Andrade, J.; Groehler, A. L.; Clark, D. E.; Muratore-Schroeder, T. L.; Pasic, L.; Smith, J.A.; Shabanowitz, J.; Hunt, D.F.; Macara, I.G.; Lannigan, D. A. (2008). Co-dependent functions of RSK2 and the apoptosis promoting factor, TIA-1, in stress granule assembly and cell survival. Molecular Cell, 31(5), 722–736
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