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    RPS6KA3

    Ribosomal protein S6 kinase alpha-3

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      Description

      RPS6KA3 is a serine/threonine-protein kinase with 83 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including cell cycle.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Ribosomal protein S6 kinase alpha-3
      • Gene ID
         6197
      • Uniprot ID
        P51812
      • Chromossomal Location
        Xp22.12
      • RNA-binding protein
        No
      • Molecular Function
        ATP binding ,cysteine-type endopeptidase inhibitor activity involved in apoptotic process ,kinase activity ,magnesium ion binding ,protein kinase activity ,protein kinase binding ,protein serine/threonine kinase activity
      • OMIM Disease
        Coffin-Lowry syndrome, Mental retardation
      • Used cell type
        MCF-7, T47D, MCF-10A, MDA-MB231, HME
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus, Cytoplasm
      • Reference
        Eisinger-Mathason, T. S. K.; Andrade, J.; Groehler, A. L.; Clark, D. E.; Muratore-Schroeder, T. L.; Pasic, L.; Smith, J.A.; Shabanowitz, J.; Hunt, D.F.; Macara, I.G.; Lannigan, D. A. (2008). Co-dependent functions of RSK2 and the apoptosis promoting factor, TIA-1, in stress granule assembly and cell survival. Molecular Cell, 31(5), 722–736
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