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    ROCK1

    Rho-associated protein kinase 1

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      Description

      ROCK1 is a protein kinase with 158 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including actin cytoskeleton organization.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Rho-associated protein kinase 1
      • Gene ID
        6093
      • Uniprot ID
        Q13464
      • Chromossomal Location
        18q11.1
      • RNA-binding protein
        No
      • Molecular Function
        ATP binding ,GTP-Rho binding ,metal ion binding ,protein kinase activity ,protein serine/threonine kinase activity
      • Used cell type
        P19
      • Used Stimuli
        Heat shock, sodium arsenite
      • Subcellular Localization
        Golgi apparatus, Cytoskeleton, Cell membrane, Cytoplasm, bleb, lamellipodium, ruffle
      • Reference
        Tsai, N.-P.; & Wei, L.-N. (2010). RhoA/ROCK1 signaling regulates stress granules formation and apoptosis. Cellular Signalling, 22(4), 668
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