menu
Explore the database
search
search
    close

    OGG1

    N-glycosylase/DNA lyase

      view_headline
      Description

      OGG1 is a DNA repair enzyme with 38 kDa. Has various molecular functions, such as endonuclease activity. Is involved in several biological processes, including aging.

       

       

       

       

       

      view_module
      Categories
      view_module
      Tags
      view_module
      Details
      • Complete Protein Name
        N-glycosylase/DNA lyase
      • Gene ID
        4968
      • Uniprot ID
        O15527
      • Chromossomal Location
        3p25.3
      • RNA-binding protein
        No
      • Molecular Function
        8-oxo-7,8-dihydroguanine DNA N-glycosylase activity ,class I DNA-(apurinic or apyrimidinic site) lyase activity ,class III/IV DNA-(apurinic or apyrimidinic site) lyase activity ,damaged DNA binding ,DNA N-glycosylase activity ,endonuclease activity ,microtubule binding ,oxidized purine DNA binding, oxidized purine nucleobase lesion DNA N-glycosylase activity
      • OMIM Disease
        Renal cell carcinoma
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus, Mitochondrion
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
      keyboard_arrow_up