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    RACK1

    Receptor of activated protein C kinase 1

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      Description

      RACK1 is a scaffolding protein with 35 kDa. Has various molecular functions, such as cyclin binding. Is involved in several biological processes, including gastrulation.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Receptor of activated protein C kinase 1
      • Gene ID
        10399
      • Uniprot ID
        P63244
      • Chromossomal Location
        5q35.3
      • RNA-binding protein
        Yes
      • Molecular Function
        Cadherin binding ,cysteine-type endopeptidase activator activity involved in apoptotic process ,enzyme binding , ion channel inhibitor activity ,protein complex scaffold activity ,protein homodimerization activity , protein kinase C binding , protein phosphatase binding ,protein tyrosine kinase inhibitor activity ,receptor binding ,receptor tyrosine kinase binding ,ribosome binding ,RNA binding ,SH2 domain binding ,signaling adaptor activity
      • Used cell type
        COS-7, HeLa, HEK293, DU145, M57
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus, Plasma membrane, Cytoplasm, perinuclear region, Perikaryon, dendrite, phagocytic cup
      • Reference
        Arimoto, K.; Fukuda, H.; Imajoh-Ohmi, S.; Saito, H.; Takekawa, M. (2008). Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways. Nat Cell Biol. 10(11):1324-32
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