PUM2

Pumilio homolog 2

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    Description

    PUM2 is a sequence-specific RNA-binding protein with 114 kDa. Has various molecular functions, such as RNA binding. Is involved in several biological processes, including regulation of chromosome segregation.

     

     

     

     

     

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    Categories
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    Details
    • Complete Protein Name
      Pumilio homolog 2
    • Gene ID
       23369
    • Uniprot ID
      Q8TB72
    • Chromossomal Location
      2p24.1
    • RNA-binding protein
      Yes
    • Molecular Function
      mRNA 3'-UTR binding,RNA binding
    • Used cell type
      Rat hippocampal neurons, HeLa, COS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Cytoplasm, Cytoplasmic granule, perinuclear region
    • Reference
      Vessey, JP.; Vaccani, A.; Xie, Y.; Dahm, R.; Karra, D.; Kiebler, MA.; Macchi, P. (2006). Dendritic localization of the translational repressor Pumilio 2 and its contribution to dendritic stress granules. J Neurosci. 26(24):6496-508
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