PTK2

Focal adhesion kinase 1

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    Description

    PTK2 is a non-receptor protein-tyrosine kinase with 119 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including angiogenesis.

     

     

     

     

     

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    Categories
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    Details
    • Complete Protein Name
      Focal adhesion kinase 1
    • Gene ID
      5747
    • Uniprot ID
      Q8IYN9
    • Chromossomal Location
      8q24.3
    • RNA-binding protein
      No
    • Molecular Function
      Actin binding ,ATP binding ,JUN kinase binding ,non-membrane spanning protein tyrosine kinase activity ,protein kinase activity ,protein kinase binding ,protein tyrosine kinase activity ,Ras guanyl-nucleotide exchange factor activity ,receptor binding ,SH2 domain binding , signal transducer activity
    • Used cell type
      U-2 OS
    • Used Stimuli
      Sodium arsenite
    • Subcellular Localization
      Cytoskeleton, Nucleus, Plasma membrane, focal adhesion, cell cortex
    • Reference
      Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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