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    PRMT5

    Protein arginine N-methyltransferase 5

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      Description

      PRMT5 is an arginine methyltransferase with 72 kDa. Has various molecular functions, such as protein heterodimerization activity. Is involved in several biological processes, including cell proliferation.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Protein arginine N-methyltransferase 5
      • Gene ID
        10419
      • Uniprot ID
        O14744
      • Chromossomal Location
        14q11.2
      • RNA-binding protein
        No
      • Molecular Function
        Core promoter sequence-specific DNA binding ,histone-arginine N-methyltransferase activity, histone methyltransferase activity (H4-R3 specific) ,identical protein binding ,methyl-CpG binding ,methyltransferase activity ,protein-arginine N-methyltransferase activity ,protein-arginine omega-N symmetric methyltransferase activity , protein complex binding ,protein heterodimerization activity ,ribonucleoprotein complex binding, transcription corepressor activity
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Golgi apparatus, Nucleus, Cytoplasm
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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