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    POLR2B

    DNA-directed RNA polymerase

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      Description

      POLR2B is a DNA-dependent RNA polymerase with 133 kDa. Has various molecular functions, such as DNA binding. Is involved in several biological processes, including mRNA splicing, via spliceosome.

       

       

       

       

       

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      Details
      • Complete Protein Name
        DNA-directed RNA polymerase
      • Gene ID
        5431
      • Uniprot ID
        P30876
      • Chromossomal Location
        4q12
      • RNA-binding protein
        Yes
      • Molecular Function
        Chromatin binding ,DNA binding ,DNA-directed 5'-3' RNA polymerase activity ,metal ion binding ,ribonucleoside binding ,RNA binding
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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