ATP2C1 is a magnesium-dependent enzyme with 100 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including actin cytoskeleton reorganization.
ATP binding ,calcium ion binding ,calcium-transporting ATPase activity ,manganese ion binding ,manganese-transporting ATPase activity ,metal ion binding ,signal transducer activity
OMIM Disease
Hailey-Hailey disease
Used cell type
COS-1
Used Stimuli
Sodium arsenite
Subcellular Localization
Golgi apparatus membrane, Multi-pass membrane protein
Reference
Yang, F.; Peng, Y.; Murray, E. L.; Otsuka, Y.; Kedersha, N.; Schoenberg, D. R. (2006). Polysome-Bound Endonuclease PMR1 Is Targeted to Stress Granules via Stress-Specific Binding to TIA-1 . Molecular and Cellular Biology, 26(23), 8803–8813