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    PKCα

    Protein kinase C alpha type

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      Description

      PKCα is a Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase with 76 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including angiogenesis.

       

       

       

       

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      Details
      • Complete Protein Name
        Protein kinase C alpha type
      • Gene ID
         5578
      • Uniprot ID
        P17252
      • Chromossomal Location
        17q24.2
      • RNA-binding protein
        No
      • Molecular Function
        ATP binding, calcium-dependent protein kinase C activity ,enzyme binding ,histone kinase activity (H3-T6 specific) ,protein kinase activity ,protein kinase C activity ,protein serine/threonine kinase activity ,zinc ion binding
      • OMIM Disease
        Pituitary tumor
      • Used cell type
        SK-N-Be (2) C
      • Used Stimuli
        Heat shock
      • Subcellular Localization
        Plasma membrane, Nucleus, Mitochondrion, Cytoplasm
      • Reference
        Kobayashi, T.; Winslow, S.; Sunesson, L.; Hellman, U.; Larsson, C. (2012). PKCalpha binds G3BP2 and regulates stress granule formation following cellular stress. PLoS One. 7(4):e35820
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