menu
Explore the database
search
search
    close

    PCNA

    Proliferating cell nuclear antigen

      view_headline
      Description

      PCNA is a protein with 28 kDa. Has various molecular functions, such as chromatin binding. Is involved in several biological processes, including cell proliferation.

       

       

       

       

       

      view_module
      Categories
      view_module
      Tags
      view_module
      Details
      • Complete Protein Name
        Proliferating cell nuclear antigen
      • Gene ID
        5111
      • Uniprot ID
        P12004
      • Chromossomal Location
        20p12.3
      • RNA-binding protein
        No
      • Molecular Function
        Chromatin binding ,damaged DNA binding ,dinucleotide insertion or deletion binding ,DNA polymerase binding ,DNA polymerase processivity factor activity ,enzyme binding ,estrogen receptor binding ,histone acetyltransferase binding ,identical protein binding ,MutLalpha complex binding ,purine-specific mismatch base pair DNA N-glycosylase activity ,receptor tyrosine kinase binding
      • OMIM Disease
        Ataxia-telangiectasia-like disorder
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
      keyboard_arrow_up