menu
Explore the database
search
search
    close

    TNKS

    Tankyrase-1

      view_headline
      Description

      TNKS is a Poly-ADP-ribosyltransferase with 142 kDa. Has various molecular functions, such as histone binding. Is involved in several biological processes, including mitotic spindle organization.

       

       

       

       

       

      view_module
      Categories
      view_module
      Tags
      view_module
      Details
      • Complete Protein Name
        Tankyrase-1
      • Gene ID
        8658
      • Uniprot ID
        O95271
      • Chromossomal Location
        8p23.1
      • RNA-binding protein
        No
      • Molecular Function
        Histone binding,NAD+ ADP-ribosyltransferase activity,zinc ion binding
      • Used cell type
        RPE-1, 293T, U-2 OS, HeLa
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus, Golgi apparatus, Cytoskeleton, Cytoplasm, centromere, telomere
      • Reference
        Leung, AK.; Vyas, S.; Rood. JE.; Bhutkar, A.; Sharp, PA.; Chang, P. (2011). Poly(ADP-ribose) Regulates Stress Responses and microRNA Activity in the Cytoplasm. Mol Cell. 42(4):489-99
      keyboard_arrow_up