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    OPTN

    Optineurin

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      Description

      OPTN is a protein with 65 kDa. Has various molecular functions, such as metal ion binding. Is involved in several biological processes, including cell death.

       

       

       

       

       

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      Categories
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      Details
      • Complete Protein Name
        Optineurin
      • Gene ID
        10133
      • Uniprot ID
        Q96CV9
      • Chromossomal Location
        10p13
      • RNA-binding protein
        No
      • Molecular Function
        Identical protein binding ,K63-linked polyubiquitin binding ,metal ion binding ,polyubiquitin binding ,protein binding, bridging ,protein C-terminus binding ,Rab GTPase binding
      • OMIM Disease
        Amyotrophic lateral sclerosis, Glaucoma
      • Subcellular Localization
        Endosome, Golgi apparatus, perinuclear region, autophagosome, Cytoplasmic vesicle
      • Reference
        Vanderweyde, T.; Youmans, K.; Liu-Yesucevitz, L.; Wolozin, B.(2013). The Role Stress Granules and RNA Binding Proteins in Neurodegeneration. Gerontology. 59(6):524-33
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