CIRP

Cold-inducible RNA-binding protein

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    Description

    CIRP is a protein with 18 kDa. Has various molecular functions, such as mRNA 3'-UTR binding. Is involved in several biological processes, including mRNA stabilization.

     

     

     

     

     

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    Categories
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    Details
    • Complete Protein Name
      Cold-inducible RNA-binding protein
    • Gene ID
      1153
    • Uniprot ID
      Q14011
    • Chromossomal Location
      19p13.3
    • RNA-binding protein
      Yes
    • Molecular Function
      mRNA 3'-UTR binding ,RNA binding ,small ribosomal subunit rRNA binding, translation repressor activity
    • Used cell type
      COS, HeLa,NIH 3T3, 293T
    • Used Stimuli
      Sodium arsenite, heat shock, sorbitol, dithiothreitol, thapsigargin
    • Subcellular Localization
      Nucleus, Cytoplasm
    • Reference
      De Leeuw F., Zhang T., Wauquier C., Huez G., Kruys .V, Gueydan C. (2007). The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methylation-dependent mechanism and acts as a translational repressor. Exp Cell Res. 2007 Dec 10;313(20):4130-44
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