menu
Explore the database
search
search
    close

    CIRP

    Cold-inducible RNA-binding protein

      view_headline
      Description

      CIRP is a protein with 18 kDa. Has various molecular functions, such as mRNA 3'-UTR binding. Is involved in several biological processes, including mRNA stabilization.

       

       

       

       

       

      view_module
      Categories
      view_module
      Tags
      view_module
      Details
      • Complete Protein Name
        Cold-inducible RNA-binding protein
      • Gene ID
        1153
      • Uniprot ID
        Q14011
      • Chromossomal Location
        19p13.3
      • RNA-binding protein
        Yes
      • Molecular Function
        mRNA 3'-UTR binding ,RNA binding ,small ribosomal subunit rRNA binding, translation repressor activity
      • Used cell type
        COS, HeLa,NIH 3T3, 293T
      • Used Stimuli
        Sodium arsenite, heat shock, sorbitol, dithiothreitol, thapsigargin
      • Subcellular Localization
        Nucleus, Cytoplasm
      • Reference
        De Leeuw F., Zhang T., Wauquier C., Huez G., Kruys .V, Gueydan C. (2007). The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methylation-dependent mechanism and acts as a translational repressor. Exp Cell Res. 2007 Dec 10;313(20):4130-44
      keyboard_arrow_up