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    SLC6A8

    Sodium- and chloride-dependent creatine transporter 1

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      Description

      SLC6A8 is a protein with 70 kDa. Has various molecular functions, such as creatine transmembrane transporter activity. Is involved in several biological processes, including creatine metabolic process.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Sodium- and chloride-dependent creatine transporter 1
      • Gene ID
        6535
      • Uniprot ID
        P48029
      • Chromossomal Location
        Xq28
      • RNA-binding protein
        Yes
      • Molecular Function
        Creatine:sodium symporter activity ,creatine transmembrane transporter activity , neurotransmitter:sodium symporter activity
      • OMIM Disease
        Cerebral creatine deficiency syndrome
      • Used cell type
        NIH 3T3, EF
      • Used Stimuli
        Sodium arsenite, heat shock, TG-ionomycin, UV treatment, TG, TG-EGTA
      • Subcellular Localization
        Membrane, Multi-pass membrane protein
      • Reference
        Carpio MA., López Sambrooks C,, Durand ES., Hallak ME.(2010). The arginylation-dependent association of calreticulin with stress granules is regulated by calcium. Biochem J. 2010 Jul 1;429(1):63-72
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