SLC6A8

Sodium- and chloride-dependent creatine transporter 1

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    Description

    SLC6A8 is a protein with 70 kDa. Has various molecular functions, such as creatine transmembrane transporter activity. Is involved in several biological processes, including creatine metabolic process.

     

     

     

     

     

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    Details
    • Complete Protein Name
      Sodium- and chloride-dependent creatine transporter 1
    • Gene ID
      811
    • Uniprot ID
      P48029
    • Chromossomal Location
      Xq28
    • RNA-binding protein
      Yes
    • Molecular Function
      Creatine:sodium symporter activity ,creatine transmembrane transporter activity , neurotransmitter:sodium symporter activity
    • OMIM Disease
      Cerebral creatine deficiency syndrome
    • Used cell type
      NIH 3T3, EF
    • Used Stimuli
      Sodium arsenite, heat shock, TG-ionomycin, UV treatment, TG, TG-EGTA
    • Subcellular Localization
      Membrane, Multi-pass membrane protein
    • Reference
      Carpio MA., López Sambrooks C,, Durand ES., Hallak ME.(2010). The arginylation-dependent association of calreticulin with stress granules is regulated by calcium. Biochem J. 2010 Jul 1;429(1):63-72
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