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    DAZL

    Deleted in azoospermia-like

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      Description

      DAZL is an RNA-binding protein with 33 kDa. Has various molecular functions, such as mRNA 3'-UTR binding. Is involved in several biological processes, including germ cell development.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Deleted in azoospermia-like
      • Gene ID
        1618
      • Uniprot ID
        Q92904
      • Chromossomal Location
        3p24.3
      • RNA-binding protein
        Yes
      • Molecular Function
        Identical protein binding , mRNA 3'-UTR binding, RNA binding, translation activator activity
      • OMIM Disease
        Susceptibility to Spermatogenic failure
      • Used cell type
        HeLa
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus, Cytoplasm
      • Reference
        Lee, K. H., Lee, S., Kim, B., Chang, S., Kim, S. W., Paick, J.-S., & Rhee, K. (2006). Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAs. The EMBO Journal, 25(18), 4263–4270
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