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    DYNC1H1

    Cytoplasmic dynein 1 heavy chain 1

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      Description

      DYNC1H1 is a protein with 532 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including cell division.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Cytoplasmic dynein 1 heavy chain 1
      • Gene ID
        1778
      • Uniprot ID
        Q14204
      • Chromossomal Location
        14q32.31
      • RNA-binding protein
        Yes
      • Molecular Function
        ATPase activity , ATP binding ,dynein intermediate chain binding , dynein light chain binding , dynein light intermediate chain binding , microtubule motor activity ,RNA binding
      • OMIM Disease
        Charcot-Marie-Tooth disease, Mental retardation, Spinal muscular atrophy
      • Used cell type
        NIH3T3, COS-7, Schneider S2R+, HeLa, BHK
      • Used Stimuli
        Thapsigargin, sodium arsenite
      • Subcellular Localization
        Cytoskeleton
      • Reference
        Loschi, M., Leishman, C. C., Berardone, N., & Boccaccio, G. L. (2009). Dynein and kinesin regulate stress-granule and P-body dynamics. Journal of Cell Science, 122(21), 3973–3982
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