DISC1

Disrupted in schizophrenia 1 protein

DISC1 is a protein with 93 kDa. Is involved in several biological processes, including microtubule cytoskeleton organization.

Complete Protein Name

Disrupted in schizophrenia 1 protein
Gene ID

27185
Uniprot ID

Q9NRI5
Chromossomal Location

1q42.2
RNA-binding protein

No
Molecular Function

Kinesin binding ,protein complex binding ,protein complex scaffold activity
OMIM Disease

Susceptibility to Schizophrenia
Used cell type

HEK293, SH-SY5Y
Used Stimuli

Sodium arsenite, sodium pyruvate
Subcellular Localization

Cytoskeleton, Plasma membrane, Mitochondrion, Cytoplasm
Reference

Ogawa F., Kasai M., Akiyama T. (2005). A functional link between Disrupted-In-Schizophrenia 1 and the eukaryotic translation initiation factor 3. Biochem. Biophys. Res. Commun. 338(2):771-776