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    EIF4A1

    Eukaryotic initiation factor 4A-I

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      Description

      EIF4A1 is a protein with 46 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including regulation of gene expression.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Eukaryotic initiation factor 4A-I
      • Gene ID
        1973
      • Uniprot ID
        P60842
      • Chromossomal Location
        17p13.1
      • RNA-binding protein
        Yes
      • Molecular Function
        ATP binding ,ATP-dependent RNA helicase activity ,double-stranded RNA binding ,helicase activity ,mRNA binding ,RNA binding ,RNA cap binding , translation factor activity, RNA binding, translation initiation factor activity
      • Used cell type
        HeLa, MEFs
      • Used Stimuli
        Sodium arsenite, hippuristanol, pateamine
      • Subcellular Localization
        Cytosol, extracellular exosome, cytoplasm, eukaryotic translation initiation factor 4F complex, membrane
      • Reference
        Mazroui R, Sukarieh R, Bordeleau ME, Kaufman RJ, Northcote P, Tanaka J, Gallouzi I, Pelletier J. (2006). Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2alpha phosphorylation. Mol Biol Cell. 2006 Oct;17(10):4212-9
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