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    EIF4E

    Eukaryotic translation initiation factor 4E

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      Description

      EIF4E is a protein with 25 kDa. Has various molecular functions, such as enzyme binding. Is involved in several biological processes, including G1/S transition of mitotic cell cycle.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Eukaryotic translation initiation factor 4E
      • Gene ID
        1977
      • Uniprot ID
        P06730
      • Chromossomal Location
        4q23
      • RNA-binding protein
        Yes
      • Molecular Function
        Enzyme binding, eukaryotic initiation factor 4G binding , repressing transcription factor binding ,RNA 7-methylguanosine cap binding , RNA binding ,RNA cap binding ,translation initiation factor activity
      • OMIM Disease
        Susceptibility to Autism
      • Used cell type
        COS-7, DU145
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        P-body, Cytoplasm
      • Reference
        Kedersha N., Chen S., Gilks N., Li W., Miller IJ., Stahl J., Anderson P.(2002). Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell. 2002 Jan;13(1):195-210
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