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    FAK1

    Focal adhesion kinase 1

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      Description

      FAK1 is a non-receptor protein-tyrosine kinase with 119 kDa. Has various molecular functions, such as actin binding. Is involved in several biological processes, including angiogenesis.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Focal adhesion kinase 1
      • Gene ID
        5747
      • Uniprot ID
        Q05397
      • Chromossomal Location
        8q24.3
      • RNA-binding protein
        No
      • Molecular Function
        Actin binding ,ATP binding ,JUN kinase binding ,non-membrane spanning protein tyrosine kinase activity ,protein kinase activity ,protein kinase binding ,protein tyrosine kinase activity ,Ras guanyl-nucleotide exchange factor activity ,receptor binding ,SH2 domain binding ,signal transducer activity
      • Used cell type
        P19
      • Used Stimuli
        Heat shock
      • Subcellular Localization
        Plasma membrane, Cytoskeleton, Nucleus, focal adhesion, cell cortex
      • Reference
        Tsai NP., Ho PC., Wei LN. (2008). Regulation of stress granule dynamics by Grb7 and FAK signalling pathway. EMBO J. 2008 Mar 5;27(5):715-26
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