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Description
FXR2P is an RNA-binding protein with 74 kDa. Has various molecular functions, such as protein heterodimerization activity. Is involved in biological processes, including negative regulation of translation.
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Categories
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Details
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Complete Protein NameFragile X mental retardation syndrome-related protein 2
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Gene ID9513
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Uniprot IDP51116
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Chromossomal Location17p13.1
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RNA-binding proteinYes
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Molecular FunctionIdentical protein binding ,mRNA binding ,protein heterodimerization activity , protein homodimerization activity ,RNA binding
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Used cell typeSTEK, HeLa, COS-1, NIH-3T3
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Used StimuliHeat shock
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Subcellular LocalizationCytoplasm
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ReferenceMazroui R., Huot ME., Tremblay S., Filion C., Labelle Y., Khandjian EW. (2002). Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression. Hum Mol Genet. 2002 Nov 15;11(24):3007-17