GLE1

Nucleoporin GLE1

    view_headline
    Description

    GLE1 is a protein with 79 kDa. Has various molecular functions, such as translation initiation factor binding. Is involved in several biological processes, including mRNA export from nucleus.

     

     

     

     

     

    view_module
    Details
    • Complete Protein Name
      Nucleoporin GLE1
    • Gene ID
      2733
    • Uniprot ID
      Q53GS7
    • Chromossomal Location
      9q34.11
    • RNA-binding protein
      No
    • Molecular Function
      Identical protein binding ,inositol hexakisphosphate binding ,phospholipid binding ,translation initiation factor binding
    • OMIM Disease
      Arthrogryposis, Lethal congenital contracture syndrome
    • Used cell type
      HeLa, U-2 OS, RPE-1
    • Used Stimuli
      Heat shock, thapsigargin, nocodazole, taxol, puromycin
    • Subcellular Localization
      Nucleus, Cytoplasm
    • Reference
      Aditi; Folkmann, A.W.; and Wente, S.R. (2015). Cytoplasmic hGle1A regulates stress granules by modulation of translation. Mol Biol Cell. 2015 Apr 15; 26(8): 1476–1490
    keyboard_arrow_up