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    EIF2AK2

    Interferon-induced, double-stranded RNA-activated protein kinase

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      Description

      EIF2AK2 is a protein with 62 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including endoplasmic reticulum unfolded protein response.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Interferon-induced, double-stranded RNA-activated protein kinase
      • Gene ID
        5610
      • Uniprot ID
        P19525
      • Chromossomal Location
        2p22.2
      • RNA-binding protein
        Yes
      • Molecular Function
        ATP binding ,double-stranded RNA binding ,eukaryotic translation initiation factor 2alpha kinase activity , non-membrane spanning protein tyrosine kinase activity ,protein kinase activity ,protein phosphatase regulator activity ,protein serine/threonine kinase activity ,RNA binding
      • Used cell type
        W4 ES, H35 , CHO-K1, tsH1
      • Used Stimuli
        Sodium arsenite, thapsigargin, tunicamycin, dithiothreitol
      • Subcellular Localization
        Nucleus, Cytoplasm, perinuclear region
      • Reference
        Harding H., Novoa Y., Zhang H., Zeng R., Wek M., Schapira M.,Ron,D. (2000). Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell. 2000 Nov;6(5):1099-108
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